duplication of genes from ancestral state

Differential expression of human duplicated genes

PREP alumnus Joseph Rosas contributed to a publication from Megan Dennis' lab on expression patterns of gene duplications in humans compared with chimpanzees. By examining the trajectory of recent human-duplicated genes, they suggest that evolutionary divergence of how these genes are regulated drives their differential expression. 

To read the open access paper, see Shew et al. 2021, Molecular Biology and Evolution.

Congratulations to Joseph, Megan, and first author Colin Shew!

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